» Cohesion Group Representative Sequences Alignment

    Subhomology Group      
Scer_Aa_|_CG-01   α         MPMDFQPTSSHSNWVVQKFGGTSVGKF--PVQIVDDIVKHYSKP----DGPNNNVAVVCSARSSYTKAEG--TTSRLLKCCDLASQES-----------EFQDIIEVIRQDHIDNADRFILNPALQAKLVDDTNKELELVKKYLNASKVLGE--------VSSRTVDLVMSCGEKLSCLFMTALCNDRGCKAKYVDLSHIVPSDFSASALDNSFYT---FLVQALKEKLAPFVSAKER---IVPVFTGFFG--LVPTG--LLNGVGRGYTDLCAALIAVAVNA--DELQVWKEVDGIFTADPRKVP-EARLLDSVTPEEASE-LTYYGSEVIHPFTMEQVIRAKIPIRIKNVQNP-----------LGNGTIIYPDNVAKKGESTPPHPPENLSSSFYEKRKRGATAITTKNDIFVINIHSNK-KTLSHGFLAQIFTILDKYKLVVDLISTSEVHVS-------MALPIPDADSLKSLRQAEEKLR-----------ILGSVDITKKLSIVSLVGKHMKQYIGIAGTMFTTLAEEGINIEMISQGANEINISCVINE--SDSIKALQCIHAKLLSERTNTSNQFEHAIDERLEQLKRLGI                                                                                                                                                                          
Hnep_Aa_|_CG-02   α                    MKRTVEKIGGTSISN---TQVVLENVLIGGRKG-----ADLYNRIFVVSAYSG--------MTNRLLEHKKSGEPGVFSLFAGAGNKWAWTEALASVAEAMEAKNAEMFSGEPEQAVADNFVRERIEDVRNCLIDLHRLCSYGQFRLDENLTTVKEVLSSLGEAHSAFNTALLLQKHGVNARAVDLTAWRDERDLTMEER---------MEDALGGIDLSSE---------LPIVTGYAS---SRDG--LVRQFGRGYTEVTFSRLAAFVQA--DEAIIHKEFH-LSSADPNLVGQDRVRKIGLTNFDVADQLSNMGMEAVHPKAAKILRQAGIPLRVKNTFDP-----------KDGGTVISADYAP------------------ENPRAEIVTGLKGVFALEVFDQDMVG----EKGYDSTILDALTRHSIRIVSKCSNANTIT-------HYIEGSRKALKRATADIETKLPG-------------AEVSTSRVAIVSVIGADIN-VPGITAKALTALHEAEVPIIGLHQVSRKTDIQAVIQE--DDFDKAICALHEALVEQVSVATPRAEALRPAA                                                                                                                                                                                   
Lcas_Aa_|_CG-03   α                      MKVVKFGGSSVA----DAGQFQKVKAIIDQD------VNRQIVVI-SAAGKYGNATRK-LTDTLYLIADGMEAG---------------RDVEPLFNQVLARLEAIN--------IALQLNVPLIKLLHTIRHHLAIRY------------SRDYLVSRGEFLTAHLMAA-----YLGYTFVD---------AANLLFFN--------KAGAIDEAKTQTAYQQLASQHGIVVPGFYG--RDADG--HVKLMPRGGSDISGAWLARLAHA--DLYENWTDVSGIKMADPRIIK-DADSIDVMSYDELRE-LTYMGFSVFQEEAVQPVRECGIPTRILNTNAP-----------EVPGTLIIHDD-------------------DPANDLKTITGIAGRKHYLVITVRKYQ-LALHLEVIQHALGVVAAHHLVVDYLPTGIDS---------FSLLIREPRRQVSVQELTAEIAA--------ACQPDKMEVTENVALIAMVSRKLRQRPAIAGKVLAYLDDNLLNVQLVSQTNDDINLLIGVHD--LDYDKAVRVIYSSIHQNFQRPAPYIEGIA                                                                                                                                                                                      
Sglo_Ab_|_CG-04   α                      MRVLKFGGTSVA----NAERFIRVADILES-----NSRQGQVAAVLSAPAK--------ITNHLVAMIDRTLNGS--------DIQPNILDAEQIFSRLLDGL-AAAQPEFDHAALRSVVEQEFAQLKQLLHGISLLKY--------CPDNVNAAIICRGEKLSIALMEALLRARGFGVTVID---PVAKLLAQGGYLES--------TVDIAES-TRHINDAAIPADHIILMAGFTA---GN-ERGELVVLGRNGSDYSAAVLAACLRA--DCCEIWTDVDGVYTCDPHQVP-DVRLLSQLSYQEAME-LSYFGAKVLHPRTIVPIAQFQIPCLIKNTTNP-----------QAPGTLIG--------------------PTS-GEEGNPVKGITHLNNMAMINVFGPG-MKEMIGMAARVFAAMSRAGSSVVLITQSSSEYS-------ISFCVPQHELAGARRALEEEFYLELKD-----GLLEPLDVISRLAIISVVGDGMRAQRGLSAKLFVALACANINIIAIAQGSSERSISVVVDN--DSTTTGVRVAHQMLFNTDQVIEVFVI                                                                                                                                                                                         
Bfra_Ab_|_CG-05   α                      MKVMKFGGTSVG----SVNSILSVKKIVES-----AGEP--VIVVVSALGG--------ITDQLISTSRMAAMGD----------AAYEGAYREIVRRHEEMVQGVIPAGETQTLLHYQVNELLDELKDIFQGIYLIKD--------LSPKTSDTIVSYGERLSSLIASRLIQG----AVWFD---SRTFIKTEKKHNKH--------TLDTELT-NRLVREAFKEIPRVSLVPGFIS---SDKVSGDVTNLGRGGSDYTAAVIAAALDA--DSLEIWTDVDGFMTADPRVIS-TAYTISELTYVEATE-LCNFGAKVVYPPTIYPVCHKNIPILIKNTFNP-----------DAQGTVIK--------------------QHVDHTKSKAIKGISSINDTSLITVQGLG-MVGVIGVNYRIFKALAKNGISVFLVSQASSENS-------TSIGVRNADADLACEVLNEEFAKEIEM-----GEISPIQAEKNLATVAIVGENMKHTPGIAGKLFGTLGRNGINVIACAQGASETNISFVVDS--KSLRKSLNVIHDSFFLSEYQVLNLFIC                                                                                                                                                                                        
Fjoh_Aa_|_CG-06   α                      MRVFKFGGASVK----DAEGIKNVYDVLQKV------GYEDVILVVSAMGK--------TTNALEVVIKNYFEKS----------EELNSSVQEIKNYHFQIVLDLFKDE--KHEVFAAVNAQFAELEYFLAHNKSP----------NYNFVYDQVVSFGELISTNILSHFMNFMGIQTQWLD---VRNFIKTNANYRDAEVD-----WETTEQNISKNVPRKQ-----LNITQGFLG--ADENN--FTTTLGREGSDYTAGIFAYCLNA--ESVTIWKDVPGVMNADPRYFE-NASLLNQISYREAIE-LAFYGATVIHPKTLQPLQKKEIPLYVKSFINP-----------LLKGTCVSKG----------------------VDLEPQYPCFIVKREQLLISLSSIDFSFIMEENISEIFGLFHEFKIKVNLIQNS-----------AISFSVCVEDKFGNFNDLN-----------------------------AILSKKFKVEYSENVTLYTIRHFTEQAAEMVE------KNKEVLLK--QVSRETMQIVTKELN                                                                                                                                                                                                    
Srub_Ac_|_CG-07   α            MESSAPASANWRVHKFGGTSLA----DPARIRHVADLLGAR-------TPPVAVVVSAMSG--------VTDRLLALAEKAHTD----------ADGLADRLQSLRDDQRAVVTDLLDGD-AAASVLRTLDQDLDDLADVLRATRLMGT--------APDTTRDLVAGYGELWSARVLGGVLRDRGLSAAVCD--AREVLVVTHEEMGPVVD------WDATQERFADWRAAH--DAPDTIVATGFIA--TTPDG--VPTTLGRNGSDHSAALFAALLEA--EALTIWTDTDGVMSADPQYVP-DARRLDGLSYEEAME-MAYFGAGVIHPRTLSPAVEHEIPITIRNTFAP-----------DRPGTRIH----------------------LNDDGASVVKGFSTIDDVALLNLEGSG-MIGVPGIARRLFDALEDEGVSVILISQGSSEHS-------ICFAVPQAQAEVAREAAEHAFYAELD-----RGQLRTVELVPNCSILAVVGDQMAGTPGVAATFFGALGEASVNVRAVAQGSSERNISAVVDR--DDARRALRAAHAGFYLSKRTLSIGVI                                                                                                                                                                                     
Ahyd_Ad_|_CG-08   α             MATEAGLKRRHVHKFGGSSLA----DPVCYRRVASILEQQA--EQQGGGRELVVVSAAG------K--TTNRLIQLVELAEAGD----------EAAGEAISALQAYQQSLIDGLLEGE-LHLELSQQLADDMQLIAKTLEGQ-------------FDRFERNGLLAFGEVWSARLLAALLTSRGDKAIWLD--ARSFLRAEDGALVKVDT-------ALSSELLKARLAEHAG----RIVVTGFIA--ADMEG--RSLLLGRNGSDYSASLLALLADG--ESTTIWSDVAGVYSADPRRVK-EARLLERLSLAEANE-LARLGSSVLHSRTLQPVADSRQRLTLRCSYNP-----------DEGCTHILRR----------------------APRSGGARIVSSVDQIALIELKVLP-QTHYEQTVAAIEAHLARHRLNPLTLQRQPDRR-------ILRLAYTLEVAQGAFELLRDFQLQG---------SFTGLIQREGYSLVALVGAGVTDNAEQCHRFYQLLADQPLEFVQVA--KDGLSLVAVLRQ--VVLEPLLIALHSALFSRPNRVGLVVF                                                                                                                                                                                         
Srub_Ad_|_CG-09   α              MMPASGRPWVVCKFGGTSVS----SRARWDTIVEVVRTH----RAEGRAPFLVCSALQG--------ISDQLEALCAQLASA---------EPGAPESTLNTIRERHRALGQDLGVEA------EAVLSGEFARLERWVDEIQATDG--------PSPRQRAAVLATGELLSTRLGAAYLSAQGLPAEWLD--AREFLRATDDPHLPPRRQYLAANCTSHADPGLQARLAD--APETVYLTQGFIA----SNALDETVLLGRGGSDTSAAHFAAKLEA--ERTEVWTDVPGLFTANPGEVP-SGRLLRRLDYDEAQE-LATMGARVLHPRCLDPARRHQIPLHVRSTEAP-----------SLDGTIVSGE---------------------GPDVGPQVKAISAKTDITAVSMDTLG-MWQEVGFLADVFQVFKHHGLSVDLMATSESN---------VTVTLDPVANALDPDILDRLLHD--------LNRYCDAELIDPCAIVSLVGRHIRSLLSELGPAFEVFDEQKVHLVTQA--ASDLNMSFVVDE--DQASRLVRELHAQFFGHRAPDAVFGPRWQELVEDGTPEETPDVWWRER                                                                                                                                                               
Ctep_Aa_|_CG-10   α                      MVVMKFGGTSVG----SAAAMRQVIANVAEKK---KSSAP--LVVLSACSG--------ITNKLIQIADAAGSGC---------LEEAQQLVGEVRQFHLDLIGELIESEELQQEVIAKIEVYLTRLERLTEGIEIVGE--------LTERSKDRFCSFGELLSTSVFAAALNEAGVSCKWID---VRTVMITDDRFGFA-----RPLAEICQKNTSEIIKPLLDAGT-VVVTQGYIG---ATESG-RTTTLGRGGSDLSAALFGAWLHS--ESIEIWTDVDGVMTTDPRIVP-EAKSIRVMTFSEAAE-LAYLGAKVLHPDTIAPAVQKNIPVYVLNTWHP-----------DSKGTLITNDPE----------------LLAGKSHGGLVKSIAVKKAQAILNIRSNR-MFGRHGFMSELFDVFERFGISVEMISTSEVSVS-------LTVD---------DAVVSEPLIKALG-------ALGEVEIEHKVATVSVVGDNLRMSKGVAGRIFNSLRN--VNLRMISQGASEINVGVVVDE--SDVQAAVASLHCEFFAESQCDAIFEKPAGS                                                                                                                                                                                     
Gfor_Ab_|_CG-11   α                      MKVLKFGGTSVG----SAVSIRNVKEIISN-L---PGDK---LLVLSAMSG--------VTNQLVEISEFVKTG---------SLDQVSEKIQALKAKHFSLIDELVPDKTSNQSIKDHIVLQLEELVEICQVQPWSNE--------VDAK----IITTGERLLTSIFSSYLKFEEVANTLLD---ARKFMK---IHNLE-----NPDTGLVGELLNDTLKSSFESN--ILITQGFVR---LNAQN-EVSTLKRGGSDYTATILGAAIRA--AEIQIWTDISGLHNNDPRFVE-NTHAVSQLSFEEAAE-LAYFGAKILHPQTISPVIGKNIPVYLKNTFTP-----------EATGTCIS---------------------ALAE--RKGLKAISAKDEITAIKIKSNR-MLMAHGFLKKIFEVFDTYETSIDMITTSEIAIS-------LTIDN---------TANLDLILQELD-------QYGEISVDASHSIICVVGEGLIEDRGTSR-LFEILQ--DVPIRMISYGGSSNNISLLVDT--RNKIEVLQKLNEKLFVNQLKSV                                                                                                                                                                                             
Susi_Aa_|_CG-12   α                      MIVMKFGGTSVE----SAAAIERVAGIVRA-R---EARRP--VVVVSAMGK--------TTNKLLAIASAAIAG---------KRNEYIPQLHDLRDYHSREARLVVPLS-ERAELDRFLDEHFQELTELVKGLAVLGE--------LTPRSIDAISSYGERLSSYIVTLAFRHFGMAAEHID---SRDVIITDRRHTQA-----APNFPETYARLQKTIPPLAAQS--VVVMGGFIG---STEDG-VTSTLGRGGSDFTAAIVGAGIQA--EEIQIWTDVDGMLTADPTILA-GGHRVKTISFAEAAE-LAYFGAKVLHPATVVPAIEKNIPVMILNSRRP-----------EVPGTHIT---------------------AHTVHCENAVKSIACKRKITTVSIHSTR-MLMAHGFLHRIFEIFDRYQTPVDMVATSEVSVS-------LTIDN---------TTHIDLVLGELR-------QFAEATVEHDSVIVCLVGENIRHTPGVARRVFNSLD--GINIRMISQGASLLNISFVIAE--TDLVNAVRLLHEEFFATLDPNVFERKEAVHA                                                                                                                                                                                    
Atha_b_|_CG-13   α       EKKTEAITEVDEKGITCVMKFGGSSVA----SAERMKEVADLILT-F---PEESP--VIVLSAMGK--------TTNNLLLAGEKAVSCG-------VSNASEIEELSIIKELHIRTVKELNIDP-------SVILTYLEELEQLLKGIAMMKE--------LTLRTRDYLVSFGECLSTRIFAAYLNTIGVKARQYD---AFEIGFITTDDFTN-----GDILEATYPAVAKRLYDDWMHDPAVPIVTGFLG---KGWKTGAVTTLGRGGSDLTATTIGKALGL--KEIQVWKDVDGVLTCDPTIYK-RATPVPYLTFDEAAE-LAYFGAQVLHPQSMRPAREGEIPVRVKNSYNP-----------KAPGTIIT---------------------KTRDMTKSILTSIVLKRNVTMLDIASTR-MLGQVGFLAKVFSIFEELGISVDVVATSEVSIS-------LTLDPSKLWSRELIQQELDHVVEELE-------KIAVVNLLKGRAIISLIGN-VQHSSLILERAFHVLYTKGVNVQMISQGASKVNISFIVNE--AEAEGCVQALHKSFFESGDLSELLIQPRLGNGSPVRTLQVEN                                                                                                                                                                         
Umet_Aa_|_CG-14   α                     MRLVMKFGGTSVG----DGARIRNVARLVKGY----QDQGNEVIAVASAMTG--------VTDKLYEMAQVAKDTC--------STSDVEKRFGELAKRHETAIHDAIQDQGIRQEVSAEIERRLSELKNALVGVCYLGE--------LTNRSLAYIYSFGERMSVPILSGALRDLGAKSKPFT--GGEAGVITDSRYESARP------DP-ITDIKVREKLLPLLQEGVIPAVTGFVA--ADSRG--IITVLGRGGSDYSASIIGAAVDA--DEIWVYTDVNGIMTTDPRIVP-EAKTLPVVTYLEAME-MSYFGAKVLHPKTIEPAVKKGIPVRVLNTFQP-----------DHPGTVVLMK--------------------DNSANCAPIKAVTMIKNIGLVNISGAG-LSGTPGIAGKIFSVLGKEDINIIMISQASSEFN-------VSMAIDGAQVDKAIAALRREF---------NGEIERDLTCDNNVCVVAVVGAGMAGSPGTAGKIFTALGKSGVNIRMISQGSSEANISFVINK--EDAQRAVKILHDEFELHNL                                                                                                                                                                                                
Mmar-6_Aa_|_CG-15   α                         MKFGGTSVG----EADCIGRVADIVESH----RSAGDEVAVVVSACSG--------ITDRIIAVADEVIASK--------EQPDIGTLLDAMRERHTRLLKETAPDH--AREVTAVIDDRLTRLQNILTAVHTLKE--------LTPRSRDYIVSFGERLSAPIVAAALRQRGIASVALD--GAEAGITTTANHGDARA------LP-VSAENIRARVAPLLAD-AVPVIMGFMG--ATEQG--VITTLGRSGSDYSAAVIGAGVDA--DEIWIWTDVDGVMTSDPRIIP-DARVLDDISYLEVME-LSYFGAKVLHPRSIEPAMQKDIPIRVKNSFKP-----------EVPGTLVLR---------------------DKHQEKRVVKAIALIEKVALVNINGAQ-MVGRPGVAKTIFSALAEREVNVMMISQGSSEAN-------ISLIIDESHLDAALGALDPLV---------EQGIVREVTYDHDVAAVAVVGAGMAGTPGTGGRIFSAIGRAGINMMMISQGSSEVNVSFVVKA--GDGKRALQVLHDEFRLSENSDD                                                                                                                                                                                             
Mjan_Aa_|_CG-16   α                     MTTVMKFGGTSVG----SGERIRHVAKIVTKR----KKEDDDVVVVVSAMSE--------VTNALVEISQQALDVR--------DIAKVGDFIKFIREKHYKAIEEAIKSEEIKEEVKKIIDSRIEELEKVLIGVAYLGE--------LTPKSRDYILSFGERLSSPILSGAIRDLGEKSIALE--GGEAGIITDNNFGSAR----------VKRLEVKERLLPLLKEGIIPVVTGFIG--TTEEG--YITTLGRGGSDYSAALIGYGLDA--DIIEIWTDVSGVYTTDPRLVP-TARRIPKLSYIEAME-LAYFGAKVLHPRTIEPAMEKGIPILVKNTFEP-----------ESEGTLITN---------------------DMEMSDSIVKAISTIKNVALINIFGAG-MVGVSGTAARIFKALGEEEVNVILISQGSSETN-------ISLVVSEEDVDKALKALKREFGDFGKKSFLNNNLIRDVSVDKDVCVISVVGAGMRGAKGIAGKIFTAVSESGANIKMIAQGSSEVNISFVIDE--KDLLNCVRKLHEKFIEKTNS                                                                                                                                                                                               
Dgeo_Aa_|_CG-17   α                  MAYSLLVMKFGGTNMQ----DAQAIRHSASLAARS----IREGVKVVVVVSAMAG--------VTNQLLGLADAAQR-G--------DIATANDEIAALRTRHFAAAQELGAAP--DSEVVREIRELHETLRQAVYGVYLLRE--------LTPRSRDLIVAFGERFSAPLMRLALEGQGLLAHHLT--GGQAGITTDTHFGNARP------LPG-TYERIRDRLGGLLAAGVTPVVAGFMG--ETEEG--AITTLGRGGTDFSATIIGKALDA--DEVWAWKDVDGVMSADPRVVP-DARNIEVLSYGEVME-LAYFGAKVLHPLAVTPLQESGIPLRVKSAADP-----------DFPGTLVQEG--------------------AHNEAGHPVKAVTAIRRVSIINVTGAG-VLGVPEVVASLFEAIARENITLLMVSQSSSMSN-------VSLAVQSADAARTLDALRRRVTG-----ELN------IEEQPGVAVLAIVGAGMRGQKGVAARLFGALAAADVNILMISQGSSELNISVALED--AQVERATRAVHAAFGLGQTAAAAD                                                                                                                                                                                           
Tkod_Aa_|_CG-18   α                        VVKFGGTSVR------DDFREAVTFVSR-----LWDENEVALVVSAIKG--------VTDALLKFSRTGEGF------------------EWIEKVHRDFAKKYGIP-------FETLAAPLRELKKLSREDFP-----------SFEAYRDHVLSYGEWLSGLAFAEALRREGIQVELFE--PWEI-LETDGNFGNARV------DIAKTSRNLKVVEEA-LERGRVAVVPGFVG---SYNG--LRTTLGREGSDYTAAVLGKGLKA--RAVLIMSGVDGIYTADPRRVV-SARLIPFVSYDELY--VASKAGMKAIHHGAIDVVR-GIPIIFGRTRD------------WSIGTIAG-----------------------YESSSLPILVHRVAGEEAVITAVGVA---EV----PGFDGE-----NGSELGIPL----------------VRLTVPSARLGSTLNL--------------------------------------------------------IHLRLIADRISPPRALSIIRG--GVSAGNV                                                                                                                                                                                                        
Aper_Aa_|_CG-19   α              VVGCAPNDLVVVKFGGSVLN----GSPGFLAAGRLVLGL----LESGLEPVVVVSAVKG--------VTDALLSSFE----------------RRDPGVGGAVGKTYLSIARELGLPP----ESVRDVSLASAEVSKLLWAAEVLGQ--------WTPRVRDLVVSYGERLSAALMAGLLRRLGVEARWLG--GGEAGIVTDGEFGDATP------LYGYTEGVIRERLEPMLEEGVVPVVAGFTG--ATREG--DTTLLGRGGSDLTATLLASALGA--GRVVLYTDVPGILSGDPRVVG-EPRRVGYMSYEEAWE-VARLGLRKFHPRTFEPLIAGGLGVEVVVSDLR-----------GRS-TRIGPGR-----------------------GGPPLKVVSLSRGVARLVVRGPSMA-GKRGFLSRLAGLLAGRGVNILAIRQPPSETA-------IELVVDERDLPAAVEELGARSGA----------AGVRLEVERGFDVVSIVGWGAVEALPEALSAAEKTGGRLLSTGELS-----PSISILARG--RTSPELARLLHRRVVESWVTG                                                                                                                                                                                              
Msed_Aa_|_CG-20   α                      MLVVKIGGSIQK----DERDFELIANRISQY-----SSRDRTIVVTSALKG--------VTNSLIEATENRDKAV--------------EIVSEIYDRHVKLLSKIVDGP-EFDNAFKSISKLADELFRIAWSIKVLDE--------ISARVRDYILSFGERMASVTLGAMLRSRKMDAQSYP----EPLLVTDDSFGEANV-----IEDLSAMEARKVLDIPS----KIVVVPGFIG----KTPTERYTTVGRGGSDYTATLLGKLLGF--PEVRLVTEVPGIMTADPRKFP-GAKTISRLSLEEAME-LAQMGAKRLHPRTFEPMFDRDIRVYIEGLYDEG--------YTLVQG---------------------------TCDSSDKLKGIAVLDDLKLISVESTN-IVGKIGSAARVMEKAREAGVNIISLSQPASETT-------IHIVVDSKNAERLSSRLQELRD-------------VDSINVQDASAVSVVGCGLRNKELFREVLREASS---FEVASISRGLRNVSATFVVKK--DEGFNLAKDLHEVVVKWIN                                                                                                                                                                                                
Ecol_Aa_|_CG-21   α                   MSEIVVSKFGGTSVA----DFDAMNRSADIVLS-----DANVR--LVVLSASAG--------ITNLLVALAEGLEPG------------ERFEKLDAIRNIQFAILERLRYPN----VIREEIERLLENITVLAEAAALA----------TSPALTDELVSHGELMSTLLFVEILRERDVQAQWFD---VRKVMRTNDRFGRA-----EPDIAALAELAALQLLPRLNEG--LVITQGFIG---SENKG-RTTTLGRGGSDYTAALLAEALHA--SRVDIWTDVPGIYTTDPRVVS-AAKRIDEIAFAEAAE-MATFGAKVLHPATLLPAVRSDIPVFVGSSKDP-----------RAGGTLVCNKTE----------------NPP------LFRALALRRNQTLLTLHSLN-MLHSRGFLAEVFGILARHNISVDLITTSEVSVA-------LTLDTTGSTSTG-DTLLTQSLLMELS-------ALCRVEVEEGLALVALIGNDLSKACGVGKEVFGVLEP--FNIRMICYGASSHNLCFLVPG--EDAEQVVQKLHSNLFE                                                                                                                                                                                                   
Ctra_Aa_|_CG-22   α               MLRQETAPLVCKFGGTSVG----TAQSIRRVCEIIQEE--------RPSFVVVSAVAG--------VTDWLEEFCRLPKGKR-------------AALTEKIRERHESIAKELG------------IEVSLAIFWEILEHFEDVEE--------LFSEDQARILAIGEDLSSTLICSYCCTYVLPLKRLE---ARQVILTDSQFLRAVP---------DLALMQTAWGELALQEDTIYLMQGFLG--ATSSG--KTTVLGRGGSDFSASLIGELCKA--RELRIYTDVCGVHTADPKILK-DTQLIDSLTFEEMQE-LASSGAKVLHQDMLKPCVRAKVPIFVTSTFN-----------VTKEGTWICASLN-------------------ESTEGPVIKALSLKSNQALWFVEYNS----PLVRLEDVLGCVRSLGFVPGVVMAQSLG---------VYFTIDWEEYPQTITKALEAFG--------------TVSCEGPLSLVALVGAKLASWS--MSRVFEALHRTPVLCWSQT----DTVINLIINK--DFGVAVTELLHDCLFK                                                                                                                                                                                                   
Srub_Ab_|_CG-47   α       MPDRSFSSTECASRPVRVLKFGGTSVG----SADGIKNAVRLVHAA----TETCRP-VVVVSAAAG--------VTDALVQAAE-----E-----SRADRGSVEAWTRRVGRRYRALAANTLADEALRARYDTALRTELSELRRALQEMA--GP--------NAAAARDVVLAAGERLMVPLLAAALDASGCTSQAVD--AATL-IRTDAAHGDATV------QWAPTR--RQVRDWHRTRAAGLPVVTGFVG--ETADG--KTTTLGRGGSDLSAAVLAWALAA--ERMERWTDVEGLYTRDPDAHS-DAQPLQRIDFEQARA-WTKAGRLGMHPCTLDPLMDAGIPLRVRCTHRP-----------AAPGTRIVP-------------------------APTLAQG                                                                                                                                                                                                                                                                                                                                                                           
Nmar_Aa_|_CG-49   α                   MTKLVVAKFGGSAIGP---NGVSIPEIIQRITNLK-----QDSKVIAVFSAPLTLDNGKKRSLTDVMLEQGRNAENG-------------VTPSLDIIKSTYEKILELVDDEN--KGKCENVIEQNLEKAKKALDEAFESKEF-------VDEVRSRALAFSGEILMSHVMNYILRSNKIKAETVD--FEDWPIITDNNIESTNFLTSE--SRTKMDKTAELVEQNE-----VVTIGGFIG--KTVDN--VTTTYERGGSDRTAADLGILFHKSYETSIDFEKDSAVVSADPKIVESGLREVHQLSYNEARL-AGMFGMKILDPIAIKEIVENGVDMPITVTNMK------------NPDKITTIKR------------------ILDEQKGHPIKIVTGKENCAIFRIETNS--------IQKLLTSLDKDKRYSEFVILSPFTKDG------IEFSRILFLDGDYVKRNEKYLLG----------FDSLATITYNRGVITLIGDEMWRVQQVASRTSAKIGEAGLNILNMDAQEETSRIIIVVEDTKDNIRKAISAIHQEISEINFI                                                                                                                                                                                               
Nmar_Ab_|_CG-50   α                     MRLVIKYGGTSIS----SAKDIRAVANHLNSL----SKKN-QIVVVCSATSG--------TTDDLIEISQSIKK-E--------NKSKAEQLASKITNRHKQLAKQTIKKADLRKKLLKNFDDDFAELVALIDGMVLLGE--------VTPRTMDYLFSFGERLSIKLVSMAVNDSGKKSVPLT--GKEVGIVTDSNFGESKP------LIDTTRLRVSKNVENLFSKKTVPVVGGFVG--ADQHG--HVTTFGRGGSDYSATIIGTCIKA--DEIWLMSDVDGLMTADPKIVK-NAKLLKEVSYIEAIE-MALFGAKQIHPRTFEPLLSKKIPMKIRSSFNL-----------KNEGTLVTAS--------------------PSPSVKNTVKCVSNVRNNGLIDIQGGS-MVGTPGTAAKIFATLAKAGINVMMISQNPSESS-------ITIVVKNADLDKAVSSLEMELLG---------KIIKKLEVTTNVAIIALIGSGMRGTVGVASKVFGAAEKNKVNVSMITQGSSELNLAFVVKN--SDTNAAVRALHNAFALDKIN                                                                                                                                                                                               
Mkan_Ab_|_CG-99   α                     MRVVMKFGGTSVG----TGESIRKVAKIVTD-----AAEEHEVIVVVSAMSG--------VTDELVRAAESAPD-W--------TEEDVKNFVGKLRRRHGKAASEAISSDLIRREVMGYVDSLLEELEKVLLGLSYVGE--------VTPRSMDLILSFGERMSAPIVAGALRDRGLEAEHLE--GGEAGVITDDGFGEAEP------ILPACRRKAQKTLIPMIESGKIPVITGFIG--RTIDG--EVTTLGRGGSDYSAAIIGCISEA--DEVQIWTDVDGVMTANPNLVP-DARTVPRLSYEEAME-LASFGAEVLHPKTVIPARSENIPIRVKNTFNP-----------ESEGTLITS---------------------ESEPSEQVVKAVASSSDVGMIDIRGTT-MIGRPGVAGRIFSRLGDEGINVIMISQSASESN-------ISIVVSRPEVRRAARIIEREF--------VGERVVERVTTYEDVAVVAVVGEGMRGTPGVASRVFRAVADAGVNIKTISQGASEVNISFVVAE--EDEAAAVNAVHSEFELGEEA                                                                                                                                                                                               
Susi_Ab_|_CG-99   α                   MKDLLVMKFGGTSVG----SAERMKVAAQLAAQE----QKKR-PVAIVVSAMSK--------VTDLLLDTMRHAEA-G--------DRAGMERNLNLLRERHEQACRELLPAS-EQGAVLAKLHDVIDEFERIVNGMAMLGE--------RPPRSVDEAVAVGERLTVVLVSEHLRVSGTPSVAVN--ARDVVVTD-AVFGNASP------LMEPTRVKARATLRPQLEQGLLPVITGFNG--ATADG--RPTTLGRGGSDFSASIVAAALDA--SELWIWTDVDGIMSADPRLVP-DAQVLEEITYAEAAE-LAYNGAKVLHPRTLAPLVEKAIPVWSKNSFAP-----------EKPGTKIVPS--------------------MAVEHG--ARAVASMRNVALVSLTPASPEVNGVQVLARALEAIARADVEVLVLTSSSYRQN-------FCVLVREDELDRSVQALESALAL-----ELAHHYVHPIEVDRNVGLLAAVGEGMQGKPGLAGRIFTAISRVQVNIIAIAQGSSELTIAVVVRR--EGLEKAVKAVHAECGLGMRPPVPVFPFGASEGRAQRPTKR                                                                                                                                                                           
Mxan_Ac_|_CG-99   α                      MRVMKFGGTSVG----NAERMRGVADLAAA-----ARKQTRVMMVASAVSG--------ITNLLLEAARAAQEGQ--------PVESLHGRFEDVHRGIIRELAPELGEA-RQRSLEEGLSTLASELRGLLQGVGLLRE--------CSPSVLAHLSGLGERAACLILGALMHARGLEPHAVE---PRDVILCAGDPLQA--------TPLQEETRARFTPLREAGGPGLMLMPGFFG---GD-TRGKTMCLGRGGSDYSAALAAAALDA--ELLEIWTDVDGIFSADPRLVP-EAFPLPEVSFEEAME-LAYFGAKVLHPKTIAPARERGIPVRVCNSFRP-----------DHPGTRVT--------------------DDA-APPEHPVRGLSFLPGIALVNLGGAG-LKGVPGTAARVFESMALANISVVLITQGSSECS-------ISFCVQQADAERAVQALEVAFEMERAA-----GKVDTIEQQRGLAVLSIVGDGMRHRVGVAGTFFSALADVGCSIAAIAQGSSERSISAVIAE--TDGPRALAHVHGRCFGTTEVVELLLA                                                                                                                                                                                         
Mxan_Ad_|_CG-99   α                        MMKFGGTSVG----SPTRLRQVVELIGK-----HARQGPLAVVVSAMGD--------TTDWLLDAAHLATEGD---------LEGALAVATRIADLAKANA-AALAPG-QATALAERVDGLLAPLRQLLHGVSLTRE--------CSAPTRDRVLSFGELVSATLLAELLTAHRTPATFRD---ARQLLVTDDRFGAA--------RVDLVRTRERLQAARETWGVEVPVLPGFIA---AT-PDGRTTTLGRNGSDYTAALVAQGLGA--SEVTVWTDVLGLHTADPELVT-DAYPVAHLTHGEGLE-LAAVGARMLHPRTMIPLIESGISLRIRNTMEP-----------EHPGTLID--------------------AIG-SRDGQRPACIATREDLALLGIEVRK-LSDQFQLGERVLAALREARVTVWMTAQSANGQS-------LAVVVPRPDAEHARSVLVTELAQELSR-----REVEPLEVRQPVTLLTLVAETMGHGVNVAGRFFSALGAVGVNVRASAQGASSRSLSCVVDA--ADTAVAARTTHAAFNLAHQQVSLFVL                                                                                                                                                                                         
ROSE-4a_|_CG-99   α                    MPLLVMKFGGTSVG----DAAAIQAVAAITEAQ----RAAWGRVVLVVSAMSG--------VTDMLIRGATTAAS-G--------DKHTFRDLDRMLREKHAAALAELVPDDQERTAIDDQIARLIDEFSILCHSVAVLGE--------LSPRAIDAISSLGERMSVRVVAAALRARGIPAEALD--ASEFVVTT-AHFGDARP------LQEVTRERTRARILPLLGRGIVPVITGFIG--ATEQG--VTTTLGRGGSDYSGAIIGAALDA--DEVDIYTDVDGVMTTDPRLAP-DARVIPVLSYAEMGE-LAYFGAKVLHPRTIRPIVERGIPLRVRNTFNP-----------YHPGTLVVQD--------------------VE-SNGQTVKAVTAIRNLSLVTVEGRG-MIGVPGVAARTFGAVASVGANVLMISQASSEQS-------ICFVVPSSTIPQVTYALEHNLAM-----ELARRDIDRIWAREDVAIVTAVGAGMRDTPGVAARVFGALADNHINVIAIAQGSSECSISTVVAA--ADCDAAVRAVHRLTGV                                                                                                                                                                                                   
Rxyl_Aa_|_CG-99   α                 MSSAEPLVIKFGGTSVG----DGEGFARAARITAGA----AAEGRPVAAVVSAMSG--------VTDALLAAAAGTATAG-----TRTARGLARDLRRALGERHLAAARCAVSGD-LLPEVEARVLSLLDRLEEELARRAL-----------PEAERRAEIAVCGERLSAEILAGALRAAGAP--AAV--AADP-IATGPGGEEVLS------EETRAR--CTRHVRPLLEEGLVAVVPGYAG--RSPDG--AVTTLGRGGSDLSATALGRGIGA--GEVWIMTDVDGVLDADPRLVP-GAATLPRLSYREAGA-FAALGAEVLHPRTMEPAAAAGIEVLVRNTFDP-----------HSPGTRISARE-----------------------CGPGLRALALRRGLS-----VEPLE-ALDGRSGDVFCLLGADVYGIRALVERPSGSA-------AAVIG--------------------------------------------VGSPGDEELAAGLRRLHRAGIRPLWAGNTA-----AGLAFVVAG--SRAEEALRELHAALLRREALAGEAVA                                                                                                                                                                                         
ROSE-4b_|_CG-99   α                      MVVMKFGAVAVS----DASRVNDLVRIVRHA----IDEGEAVVVVCTAIAD--------LTNLLIGAGRAAARG---------NLTAAEQARRELWQRHRTLAERLVTDDWERETLYRAWADLLKSFDRIVRAIATLGE--------HSPRSSDAVAAIGERFIGLLLAVALRRGGVAAQLID---GAELIVTDDHFGNARP------LPEETTARARARLLPLTQSRIVPVVTGYIG--ATRQK--ITTTLGRGGGDYSATLIAAALEA--DEVVIWTDVPGILTADPKLVP-EARTLPELSYIEATE-IATLGAEVLHPRSLTPLANRNIPLHIRSLEQP-----------HIPGTRIVAA-----------------PHISSDTARTIISAPSISLIEISMSPLAAAELGWAPDLAARILAELTGCGIEVLTFAQSFSERG-------LVLAVRATDAEYAYERIEACLQPERD-----SKALRAISLRAPVALVAVISAPESTR--LAPRALTALARVQGTVLAMVHGNTSRHLSFIVPE--EELSAVVRALHRELMAG                                                                                                                                                                                                  
Msta_Aa_|_CG-23   α                    MGIVVAKFGGTSVG----SGERIYKAANSVVNE----YMQGNQVVVVVSAINK--------TTDESIKLVNESIGEL------------------------------------------------------------------------VTEKQLAGILSMGEMQSVRIMAATIESLGVKAEFIDPFSEKWPVITDSNYLNAKI------DKKETQKRVTKYIKKLLNQGIIPVVCGFLG--CDVDG--SVTTLGRGGSDVSAFLIGHCLGA--DEVVIVTDVKGVMSTDPRKLN-TARKLDKITVEEMID-LANYGAQVLHPNALRYKDPNIKAKIISFEYGDLR----------VQGTDIIGPAH-------------------EEYDVITITKCDDKLSVLAVVGENLM---NQQCIIAQITQKVCENKLNIYGISTGESS---------ITLFFKEDEAIKAHEKLHDLVIG--------GDTLSSISLGQKIAMISVVSHDFIDTPGIIASITKPLHENEINIVELS--SSQTAVVVFVDW--NDGDKAYDLIKETLQ                                                                                                                                                                                                    
Mmar_Ac_|_CG-52   α     MALPDQPQPDQADRPLKLCVLKFGSSVLF----KPDDYARAAHEIYRH----VRAGEKVVAVVSALDG--------ETDALFGVGNDVGQG-------------------------------------------------------------------------CSDALLARLVRCGELKSAALMGLALERSGIPSAVLD--PHEMGLRAEGEALDANL------TGLDASRVLKRFASVD-----VIVAPGFFG--EGADG--PVT-LGRGGTDLTAVEFAHWLGA--DRVRLIKDVDGVYTDDPAKVA-NAKRFDQLDYDEAAR-VSR-GLVQDKAITRAKEQDVVIEVAALGRP-------------YATRIAAVEQR-------------------AGD-------GLEMKPMRVAVL-GHG------------------------------------------------------------------------------------------AVGAGVCAHLLAHPGRFTLNPVLVRDPAQHS--AGAAAELSFTDD--PARALG                                                                                                                                                                                                             
           
Mthe-3_Ab_|_CG-24   β                    MKVLVQKFGGTSVA----SPEQRLVVTGHIERA----CRVGYQVVVVVSAMGRRGAPY---ATDTLLELLGDNEVE---------------------------------------------------------------------------PRERDLLLACGEVISGVVLTGLLKSKDLPAVFLT--GGQAGIITDAQFGDARI------LRVEPRRIQSYLDQGR-----VVVVAGFQG--VTESG--EVTTLGRGGSDTTAVALGVALGA--EAVEIFTDVDGVKTADPHIVS-DARTLSTITYNEVCQ-MAYEGAKVIHPRAVEIARQKNIPLRIKSTFN------------DGPGTLVVAWQPGVTG--------------VHISRDRVITGITHMDGLTQLRVS-LP---SGEG-AGEVFPLLAQNNISVDFINIFPG---------ELVFTVKSEVARQARELIEG--------------LGLKVTARPGCAKVATVGAGMRGVPGVMATIVTALEREGIKILQSA--DSYTSIWCLVDR--KDMERAVQTLHREFKLNDGKTG--------EVKVYAVG                                                                                                                                                                             
Cglu_Aa_|_CG-25   β                    MALVVQKYGGSSLE----SAERIRNVAERIVAT----KKAGNDVVVVCSAMGD--------TTDELLELAAAVNPV-------------------------------------------------------------------------PPAREMDMLLTAGERISNALVAMAIESLGAEAQSFT--GSQAGVLTTERHGNARI------VDVTPGRVREALDEGK-----ICIVAGFQG--VNKETR-DVTTLGRGGSDTTAVALAAALNA--DVCEIYSDVDGVYTADPRIVP-NAQKLEKLSFEEMLE-LAAVGSKILVLRSVEYARAFNVPLRVRSSYS------------NDPGTLIAGSM------------------EDIPVEEAVLTGVATDKSEAKVTVLGIS---DKPGEAAKVFRALADAEINIDMVLQNVSSVED--GTTDITFTCPRSDGRRAMEILKKLQV---------QGNWTNVLYDDQVGKVSLVGAGMKSHPGVTAEFMEALRDVNVNIELIS--TSEIRISVLIRE--DDLDAAARALHEQFQLGG------------EDEAVVYAGTGR                                                                                                                                                                         
Tmar_Ab_|_CG-26   β       RVAKYKVLGGAEKFSVVVMKFGGAAIS----DVEKLEKVAEKIIKR----KKSGVKPVVVLSAMGD--------TTDHLIELAKTIDEN-------------------------------------------------------------------------PDPRELDLLLSTGEIQSVALMSIALRKRGYKAISFT--GNQLKIITDKRYGSARI------IDIN-TDIISRYLKQDF----IPVVAGFQG--ITETG--DITTLGRGGSDLTAIALAYSLGA--DLCELYKDVDGVYTADPRIVK-DARVIKELSWEEMIE-LSRHGAQVLQARAAEFARKYGVKVLIKNAHK------------ETRGTLIWEGT---------------------KVENPIVRAVTFEDGMAKVVLKDVP---DKPGVAARIMRTLSQMGVNIDMIIQG-MKSGE---YNTVAFIVPESQLGKLDIDLLKTR-----------SEAKEIIIEKGLAKVSIVGVNLTSTPEISATLFETLANEGINIDMIS--ASSSRISVIIDG--KYVEDAVKAIHSRFELDRE                                                                                                                                                                                                
Adeh_Aa_|_CG-27   β                    MPVVVQKYGGSSVG----TVEKMRKVAEKVAAA----RRAGKDVCVVVSAMGD--------TTDDLLSLAKQISPA-------------------------------------------------------------------------PARRELDMLLSAGERISMALLSMALNDLGVPAISFT--GSQSGIITTDSHSAARI------LEVRAFRVQEELAKGK-----VVIVAGYQG--VSTRK--EVTTLGRGGSDTTAVALAAALG---ADCEIYSDVAGVFTADPRVVP-SAARLEALSYEEMQE-LAAAGAKVLNAQAVEFAKERGIAIHARSTFG------------GPEETVVK---GG--------------------AHPERIAGVAMQKGLALLGF--------PAARLGDVLAILERHGAVALEIAVPGERAG-----VALDLENVHDWPVLRAQ------LA--------AEVPGLAAEDEAIGAVSVVGTGISAGHRVLRAVTATLAELGARPRALF--TSPLRVTAYCDA--AVLKDAARRLHEQLVG                                                                                                                                                                                                   
Cbot_Ba_|_CG-28   β                    MATIVQKYGGTSVA----TVEKIKNVAKFIVKR----KREGNDIVIVVSAMGH--------TTDNLINLAKDISNV-------------------------------------------------------------------------PDKRELDALISTGEMVSSSLLSMAIKELGEDAISYT--AYQINISTNGQHGKSLI------NDIDKKKIDKSLKEGK-----VVVVAGFQG--INCDG--NITTLGRGGSDTSAVAIAAKLNN--AICEIYTDVDGIYSVDPRVYD-RAKKLDYIDYEEMLE-LSSLGAQVMHSRSIELAEKYNIPIYVGLSNSN------------IKGTVIRRMNN-------------------MNMEMKSVTGLATSDDDVAITMEDIN---ENINIVADIFSKLAEKQINVDMISQTAPINSR----ISLSFTIP---KEDLQEGMK-IIRN--------YASKDKIKIDENLTKFSIVGIGMKNTSGVAAKMLKIFSDNNIKVKMIT--TSEIRITCAINV--RDKINAINLVVKEFNL                                                                                                                                                                                                   
Tpet_Aa_|_CG-29   β                    MNVVVQKYGGSSVA----TPERIKNVAQRIKKK----VDEGYKVVVVVSAMGK--------TTDNLIKLAKEISPK-------------------------------------------------------------------------PDSRELDMLLATGEQVSAALLSMALKDLGIKAKSLN--AFQVKIKTTSHHTSARI------VDIDDSVIWENLKDYD-----VLVVTGFQG--VNEHG--DLTTLGRGGSDTSAVALAAKLR---VPCEIYSDVDGIYTCDPRVHP-RAKKLAYITYDEALE-LTALGAKVLHSRSVEIAKKYGIPIYCASSFTE------------EEGTMVVERLP-------------------EWLEEPVVTGATISHGQIKVSISFLP---KDVKYITAIFEEVGKKALNVDMIS-LVPSNGK----IFLSFTILEDHKEDLDEALK-EALR--------DVEGWKSTYEGGFAKLSIVGVGMRTSPGVAARFFEALERAGVTPELVT--TSEIKISCLVPE--EKAEEALKSVIEEFEL                                                                                                                                                                                                   
Ssap_Aa_|_CG-30   β                  MNLERSVLKFGGSSVS----DFTKIKNIAEMLSLR----IAQGEQLIVVVSAMGK--------TTDELMANVSTLTTS-------------------------------------------------------------------------PKDQELALLLTTGEQQTVSYLSMVLNDIGVRAKAMT--GYQAGIKTVGHHLKSRI------AEINPETFEQAFEEND-----VLVVAGFQG--INDDL--EVTTLGRGGSDTTAVALAASNH---TPCEIYTDVDGVYATDPRLYK-DAKRLDYVSYEEMME-MSALGAGVLETRSVELANNYNIPLYLGRTLSN------------VKGTWIMPQT--------------------EILEKKAVTGVALDTHMMHVTISYPL---PDNKLLTKLFSQLEDGSVNVDMISQIVNLEG-----LQMSFTIKDTDVAQISSILE-TLKE--------DFSALDFRINEEYVKISLIGSGMRDMSGVASKAFITLIENDISFYQTT--TSEISISCVIDA--ENGERAVQTLYQAFDI                                                                                                                                                                                                   
Lint_Aa_|_CG-31   β                   MTNIIVQKYGGTSVG----TPERIQNVAKRIKSY----HDKGQQVAVIVSAMGH--------TTDELVDLAAKISSN-------------------------------------------------------------------------PPKREMDMLLSTGEQISTALLAMALWEIGVPATSFT--GSQIKLLTDGNFSNAKI------KMIDRSRIDSALNEGK-----VVIIAGFQG--IDAEE--NITTLGRGGSDTSAVAVAAILGA--KECEIYTDVDGVYTADPRVVP-SAKKHKQITYEEMLE-LASLGAGVLHSRSVELGMNYDVVIHVRSSFND------------NIGTLVVSEDK--------------------IMEKLKVSGVTAKNDQARITIAGVP---DKPGLAAGLFGELSSKHILVDMIVQ-SSPHNG---INTISFTIPKKDVHEAKPILE-GFSK--------SHNAKEPEINENIAIVSAVGVGMKSHVGVAAGMFKALADNGINIEMIS--TSEIKISCVIAE--SQAKIAVNKIHDVFGLSS                                                                                                                                                                                                 
Bhal-1_Aa_|_CG-33   β                    MSIIVQKYGGTSVG----SVQRIEHVANRIIAT----AASGKKVVVVVSAMGK--------TTDELVGLASEITDE-------------------------------------------------------------------------PRKREMDMLLATGEQVTIALLAMALHKRGQEATSLT--GWQAGMITESHHGNARI------LEVERARMDELLDKVH-----VVIVAGFQG--IDQQG--EIMTLGRGGSDTSAVAIAAALKA--ERCEIYTDVTGVFTTDPRVVK-QARKLQTISYDEMLE-MANLGASVLHPRAVEFAKNYEIPLLVASSMVD------------EPGTMIEEEG--------------------TMEQNLLVRGIAFENDVTKVTVHGLP---NEIHTLPTLFAHLSAAGINVDIIIQNQTDSG-----MAISFSITQSSLKETLARLE-ELKG--------ELSFQGIDYEEELAKVSIVGSGMVSNPGVAAKMFEILAANDIAIKMVS--TSEIKVSAVIDE--ELMVLAVEMLHEQFKLHEEEPAVAVKV                                                                                                                                                                                        
Ddes_Aa_|_CG-34   β                    MRILVQKFGGTSVA----NLECMQQVKQKVLHA----RENGYKVIAVLSAMSG--------ETNRLLNMAGQWSQC-------------------------------------------------------------------------PDEAEVDALISTGEQVSVSLFAMLLQNEGIKARSVL--GFQIPLKTNTAYSRARI------LDIRKDTLVELLEAHD-----VLAVAGFQG--INDDN--RITTLGRGGSDTSAVALAAALGC--E-CEIYTDVDGVYTTDPNMCS-AARKLDRISYDEMLE-MASMGAKVLQIRSVEFAKKYKVPVRVRSTFT------------NDSGTLLTQE--------------------DSQMEAVMVSGIAYDKDQARITLRGVP---DTPGVAASLFCPLADAGIVVDMIVQN-PSLD---GVTDMTFTVPRKDLTRALELVEKTRA---------EVGAKEVLHDLNVCKVSAIGVGMRNHSGVASKTFATLRRENINILMIS--TSEIKITCLIEE--KYTELAVRTLHDAFGLDKD----------QSQAG                                                                                                                                                                                 
Cjej_Aa_|_CG-35   β                     MLIVQKYGGTSVG----TLERIEAVANRVIQS----AQQGNQLVVVVSAMSG--------VTNTLIEQAEYFSKT-------------------------------------------------------------------------PNGKDMDMLLSSGERVTSALLSIALNEKGCPAISFS--GRKAGIITDSVFTKARI------HHIDTKAIKSELQNGK-----IVVIAGFQG--VDEEG--NVTTLGRGGSDLSAVAVAGALNA--DLCEIYTDVDGVYTTDPRIEP-KAKKLDKISYEEMLE-LASLGAKVLQNRSVELAKKLNVNLVTRSSFNN------------NEGTMITKEDG---------------------MEQALVSGIALDKNQARVTLRNIE---DKPGIAAEIFSVLANENINVDMIIQ-NVGVDG---ATNLGFTVPQNELELAKNAMQ-KILS----------SKTTIESDSAVLKVSIVGVGMKSHSGVASKAFKALADEGINIGMIS--TSEIKISMIVHE--KYGELAVRALHECYGLDK                                                                                                                                                                                                 
Pcar_Aa_|_CG-36   β                    MALVVQKYGGTSVG----DVDRIRNVARRVAKT----YDDGNDVVVVVSAMSG--------ETNKLVALANELCDF-------------------------------------------------------------------------PSEREYDVLVSTGEQVTIALLSMCLQSMGYKAKSYL--GHQIPIFTDSTFSKARI------ESIDDKNIREDLNNGT-----IIVVAGFQG--IDHDG--NLTTLGRGGSDTSAVAVAAALKA--DVCEIYTDVDGVYTTDPRIVA-DATKIEKISYDEMLE-MASLGAKVLQIRSVEFAKKYGVIVHVRSSFN------------DNPGTLVTKE--------------------DEDMETVLVSGVTYNKDEAKISVMGVP---DKPGVAAKLFTPLTTSNITVDMIIQNVSNDG----LTDLTFTVPRGDFKKALKAVEETAR---------EIGAAGVRSDENIAKVSIVGVGMRSHSGIASKMFRVLSQEGINIQMIS--TSEIKVSCVIDA--KYTELAIRVLHQAFGLDK-----------KDSKAE                                                                                                                                                                                
Rrub_Aa_|_CG-37   β                    MARIVMKFGGTSVG----DVDRIRNVARRVKAE----VDAGNEVAVVVSAMSG--------ETNRLVGFCDSMTNM-------------------------------------------------------------------------YDAREYDAVVATGEQVTIGLLAIALQDIGVEARSWM--GWQIPIHTDEAHGKARI------LSIDTTVLEQRLASGQ-----VAVVAGFQG--LGPNN--RVTTLGRGGSDTSAVALAAALKA--DRCDIYTDVDGVYTTDPRIVP-KARKLDRITYEEMLE-QASLGAKVLQTRSVEMAMKHRVRVRVLSSFS------------DAPGTLVCDE--------------------DEIVEKELVSGIAYSRDEAKITLVKVS---DRPGVAARIFGPLADANINVDMIVQNVSEDG---HSTDLTFTLPRSDLARALKVLEGARD---------DINYRELTTSSAVVKVSVIGVGMRSHAGVAQTMFRALSEKGINIHVIS--TSEIKVSVLIAE--EYMELAVRALHSAYGLDA------------A                                                                                                                                                                                    
Wend_a_|_CG-38   β                   MDKIIIKKFGGTSLT----DLNR---VANLIKND----IEKGCNVIVVVSAVAG--------FTDQMVFQARQISNLSY-R---------------------------------------------------------------------QELSEYDVMLSAGEQISCGLLAITLQSIGVNAKSWL--AWQLPIVTDDFYSESKI------KTIKIERVKRSFAEGYT----AAIIAGFQG--IN-DD--RITTFGRGGSDISAVAFAVAFGV--RTCEIFTDIDGIYTADPRIVP-KARKLKFISYDEMLE-MSSSGAKILHNRSVQLAMKHNIKVQVLSTFK------------EVEGTTVLHKR--------------------DVLERYLITGITYSTNEALVTFTNLA---NN----LRTLRDIAGANVKIDMIHG-------------SSFVISKFDIDLMEKLLNKNE---------------NYAINDNVAKISIIGIGVMSNTEVMHRTLKVLSEKKIEILAIT--TSEIKISIIVQK--ECAVALVKDLHTEYELDMQH                                                                                                                                                                                               
Sama_Aa_|_CG-39   β                   MTKIYVKKFGGTSVG----TFERIEAVADAIAKA----HFEGERQVLVLSAMAG--------ETNRLYAMAANIDPL-------------------------------------------------------------------------APARELDMLVSAGEQVSIALMSIALARRGVNARSLL--GSQVKVRTNSQFGRASI------ESVDTGLLMQLLDEGA-----VPVIAGFQG--VNEQG--DVTTLGRGGSDTTAVAIAAALEA--AECQIFTDVTGVFTTDPNIDP-DAQKLDSISFEAMYE-MARQGAKVLHPDSVACARRHGVVLRVLSSFESG------------SGTLIRFDE--------------------PEHSGSGIVGIAVTRGQGLVSVAGLV---DQPQAEVALFQALANASVDTDLVVQLAEEK-------ALAFTLAQGALDKVLTLID-RLAL--------EQPLADVRHESPLAKVSLVSTGKAVMAEVGARVTELLEAQNIRVKLLS--TSEIKLSVVIDE--VHLQHAVRSLHRAFDLNKV                                                                                                                                                                                                
Nmen_Aa_|_CG-40   β                    MALIVHKYGGTSVG----SPERIKNVAKRVAKA----RAEGHDIVVVVSAMSG--------ETNRLVALAHEMQEH-------------------------------------------------------------------------PDPRELDVVLSTGEQVTIGLLAMALKDIGVEAKSYT--GWQVALKTDTAHTKARI------ESIDDEKMRADLAAGK-----VVIVAGFQG--ISSEG--DISTLGRGGSDTSAVALAAALKA--DECQIYTDVDGVYTTDPRVVP-EARRMDTVTFEEMIE-LASLGSKVLQIRSVEFAGKYKVRLRVLSSLQD-----------GGNGTLITFEE-------------------DDNMERAAVTGIAFDKNQARINVRGVP---DKPGVAYQILGAVADANIEVDMIIQNVGSEG----TTDFSFTVPRGDYKQTLEILSE---RQDS-----IGAAS-IDGDDTVCKVSAVGLGMRSHVGVAAKIFRTLAEEGINIQMIS--TSEIKVSVLIDE--KYMELATRVLHKAFNLG                                                                                                                                                                                                  
ACIN-1a_|_CG-41   β                    MALIVQKYGGTSMG----TPERILNVARRVKRW----HDHGHKVVVVVSAMSG--------ETNRLLALAKAITDT-------------------------------------------------------------------------PDPRELDQMVSTGEQVTISMLAMALNSIGVEAKSYT--GRQVGIKTDSAYNKARI------EAIDTDVMTKDLDAGR-----VLVVAGFQG--VDEEG--NTTTLGRGGSDTTGVALAAALKA--DECQIYTDVDGVYTTDPRVAP-KAKKVDRISFEEMLE-MASLGSKVLQIRSVEFAGKYQVPLRVLSSFDNDNDGAFDEEFKQNVGTLITTEA-------------------EDTMEQPIISGIAFNRDEAKLTILGVP---DEPGIAAKILVPISAANIEVDMIVQNVEED----GTTDFTFTVNRGDLAKAKKILEETAS---------NIGAREVSTRDDIVKVSIVGVGMRSHAGVASKMFMALAEESINILMIS--TSEIKVSVLIEE--NYLELAVRTLHTAFGLDR------------EHGESSARA                                                                                                                                                                            
Voku_Aa_|_CG-42   β                    MALIVQKYGGTSVA----SVERIQAVAQKIKAF----KEKGHQLVVSVSAMSG--------ETSRMTALAQTIQDI-------------------------------------------------------------------------PSLREMDVLLTTGEQVTIALLTMALQQLGCDAVSYT--GPQVCIMTDSEHGKARI------KSIDNHRIFHSLDQGK-----VVVVAGFQG--VDENG--HITTLGRGGSDTTAVALVTALKA--DECQIYTDVDGVFTTDPRIEI-NARRINVVSYEEMLE-MASLGSKVLQIRSVEFASKYKVPLRVLSSL-----------IDNPLGTLITRE--------------------ENIVEQVVISGIAHNKDEAKLSLIGVL---DEPGIAFKILNPISSANIEVDMIVQSVSARE---GLTNFAFTVHRNNFKTASKILNNVCK---------EIGAIAVQSDDKVVKVSLVGIGIRSHAGIATQMFEVLHNEGINIQMIS--TSEIKISVVIDE--KYLELAVRSLHAVFELDK------------E                                                                                                                                                                                    
Pput_Aa_|_CG-43   β                    MALIVQKFGGTSVG----SIERIEQVAEKVKKH----REAGDDLVVVLSAMSG--------ETNRLIDLAKQITDQ-------------------------------------------------------------------------PVPRELDVIVSTGEQVTIALLTMALIKRGVPAVSYT--GNQVRILTDSSHNKARI------LQIDDQKIRADLKEGR-----VVVVAGFQG--VDEHG--SITTLGRGGSDTTGVALAAALKA--DECQIYTDVDGVYTTDPRVVP-QARRLEKITFEEMLE-MASLGSKVLQIRSVEFAGKYNVPLRVLHSF------------KEGPGTLITIDE-------------------EESMEQPIISGIAFNRDEAKLTIRGVP---DTPGVAFKILGPISASNIEVDMIVQNVAHD----NTTDFTFTVHRNEYEKAQSVLENTAR---------EIGAREVIGDTKIAKVSIVGVGMRSHAGVASCMFEALAKESINIQMIS--TSEIKVSVVLEE--KYLELAVRALHTAFDLDA------------PARQGE                                                                                                                                                                               
Deth_Aa_|_CG-44   β                    MAVVVHKYGGTSVG----DAERIKHVAKRIIAA----RQKGSDVVAVVSAMGD--------TTDDLIALAHKLNDC-------------------------------------------------------------------------PEPREMDVLLSTGEIVSSTLLAMALKNMGQDAISLS--GQQAGIRTDSAHSKARI------TGIDPKRIHDELAKGR-----VVIVAGFQG--VSDCQ--DVTTLGRGGSDTTAVALAASLGA--SICERYTDVDGVYTADPRLIP-DARRLAEISYEEMLE-LSSYGAKIMHPRAVEIGQVYNIPILVASSFNE------------NPGTLIHGGE--------------------NMEIRNRVSGIAHDFEVAKITILGVP---DKPGIAAGLFAPLAKAGVSVDTIVQNSSQ-DHIT---DLTFTVTKSDLGKALEVIG-PIAK--------DIQAREVLSDSRIGKVSIIGTGMLNAPGYAARMFKALSDAGINILLIS--TSEIRITCIIEE--DKVKDAVKAIHKAFEMEKD                                                                                                                                                                                                
Dred_Ab_|_CG-45   β                     MLVVKKFGGSSVA----DPERIKRVARRVVEE----HQKGNQVVVTVSAMGD--------TTDDLVSLAKQVTND-------------------------------------------------------------------------PSEREMDMLLSTGEQISIALLSMAIRDLGSDVISLT--GGQVGIYTDDVHSKAKI------LKIETSRVKEELEQGR-----VVVVAGFQG--IKSNH--DITTLGRGGSDTTAVALAAALKA--DICEIFTDVDGVYTTDPRLVP-EASKLKNISFDEMLE-LASLGAQVLHPRSVELAKQYGIPIHVRTSFD------------HREGTIVEEAP--------------------NMENAPVVSGVAHDYNVAKIGLFDVP---DQPGVAKKIFKALSKHNLNVDMIIQSAMR-NNMN---DIGFTTTQDDLRKALQTIE-AIQQ--------EVGFRGYNHDEDVAKVSIVGAGMISHPGVAADMFEALADEGINLEMIT--TSEIKVSCVIKR--SETEKAVKALHKKFKLDNLAEASIYNR                                                                                                                                                                                        
Aehr_Aa_|_CG-46   β                    MALIVQKYGGTSVG----TTERIKNVARRVQAS----RERGDDVVVVVSAMSG--------ETNRLLALAEEIGPN-------------------------------------------------------------------------PPAREVDVLVSTGEQVTIALLTMALESIGTPARCYT--GPQVRILTDSAHSRARI------LDIDAKQINDDLRLGR-----VVVVAGFQG--VDESG--AITTLGRGGSDTTAVAIAAALKA--DECQIYTDVDGVYTTDPRVVP-KARRLERITVEEMLE-LASLGSKVLQIRSVEFAGKYKVPLRVLSSF------------KEGPGTLITYE--------------------ENPMEEPLISGIAFNRDEAKLTVLGAP---DVPGIAASILGPISDAGIEVDMIIQNVSTS----GATDFTFTVHKRDYEQALKILQDNKD---------KLGAREIYGDPKIVKLSLVGVGMRSHAGVASTMFKALSAEGINIQMIS--TSEIKISVVVDE--KYLELGVRTLHTAFGLDD------------ENAQVEVEGDNA                                                                                                                                                                         
Asal_Aa_|_CG-48   β                    MALYVQKYGGTSVG----TLERIEAVAERVQLT----RAQGHDVVVVVSAMSG--------ETNRLLGMAQRLDPD-------------------------------------------------------------------------ANRREMDVLVSTGEQVTIALLAIALNKRGCAAVSMT--GDQVRIHTDSAYGKARI------SHIDTEQVQAELGAGK-----VVVIAGFQG--RDEHN--AITTLGRGGSDTTAVAVAAAIKA--DECQIFTDVDGVYTTDPRIEP-KARRLSTITFEEMLE-MASLGAKVLQIRSVEFAGKYRVPLRVLSSF------------VDGEGTLITYG--------------------GERMEAPLVSGIAFNRNEASLTILGVP---DRPTVAAQILNPISDANIDVDMIVQNTLGD----GTADFTFTVNRDDYRRARALLEETAS---------ELGAACVQGNGEIAKVSIVGVGMWNHPGVARTMFKVLGEEGINMQLIS--TSEIKISVVIDE--KYLELAVRALHAAFGLDN------------EPHEQPLGNNP                                                                                                                                                                          
Mmar_Aa_|_CG-51   β                   MTRV-VAKFGGTSVG----TIERIRHAAGLVADA----ARRGETMTVVVSAMAG--------ETDRILGLAGAFGSG-------------------------------------------------------------------------LGDRETDVALAAGEQVSSALMALALREAGLEAQSFL--GWQLPVITDGPPGASRI------AGMDVAVLEAAIDAGI-----IPVVAGFQG--ITETG--EVRTLGRGGTDLSAAALAAALQA--R-CDIYTDVDGVYTTDPRVEP-DARRLDTISHDEMLE-LAAQGAKVLQTRSVEFAKARGVPMRVLSSFLEAG---------ASRGTDVVSEQ--------------------AIAERRLVSGVAYARDQARIALHGAS---NRSDMAARCFASLAEAEVGVDMIVQAHARQPG---TVTLEFSIAHRDLDRAQAVLE-DAMT--------G---VRISAETGLAKVSVVGAGLRQRADVARSLFAVLGDQDIAVKVLA--TSEIKISALIEN--DAVERAVRALHAAYGLDQV                                                                                                                                                                                                
Pmar_Ca_|_CG-32   β                    MALLIKKFGGTSVE----DITKIKAIAQSIIQS----KEAGNDIVVVVSAMGH--------STDHLNKLAESISKN-------------------------------------------------------------------------PNSRELDMLLSTGEQVTMALLSMSLNEYGIPAISLT--GSQVGIVTESIHGKARI------LDIKTERIQNYINQGY-----VVVVAGFQGSTLSHTGSMEITTLGRGGSDTSAVALSTALGA--ETCEIYTDVPGVLTTDPRIVP-NAKLLDIISCEEMLE-LASVGASVLHPRAVEIARNYGIKLYVKSSQA------------LSNGTLLHSKIKPLALKRGG------------LELTKTVNSLEVLEKQTVFSISKLP---DRPGIAAQIFETLSKANINVDLIIQATHDGKSN----DIAFTVNDFELTKTIDQCKLITK---------QLGGEYDFK-KNMTKLSIQGAGIMGRPSVSADLFDTLFQANINVRLIA--TSEIKVSCVIDI--ENISKAIRFVSEKFKLSDKQIFINPVI---------------------ESEDQPEVRGIALDKNQVQVSIRNLPDKPGVAASICLALAENNLIFDTIVQSERLTSLKTKDISFTMSKQDRERANTIFHSLTKKLAGSFIEDGPAIAKVSTVGAGMAFKVGTAGKIFRALANKNINIEMIATSEIRTSCIVLEQDCDQAVNAIHSYFQLDK 
Rbal_Aa_|_CG-99   β                    MSLIVQKFGGTSVA----DTEKIRAAARKAIRA----QKAGHRVVMVVSAMGK--------NTDTLLDLASQISDE-------------------------------------------------------------------------PPAREMDMLLSTGEQVSVALVAMAIHSMGSKAVSLT--GGQIGLKTDNSFSKARI------QSIDTGRIERLLDAGN-----IVVAAGFQG--IDDDL--NITTLGRGGSDTTAVALAAVLGA--DACEINTDVDGVYTTDPRLLA-EARRVDVISYDEMLE-LASLGAGVMHSRSIEFAKKFEVPIHVRSSFS------------DQDGTMIVAQ---------------------PESETAPVSGAALTRDEARVTVLGVP---DVPGMSQKIFSAIAAQKVAVDMVVQNVGTS----GKADVSFTVAGGELKKTLAALEGILD---------SLGADGVTHDDQVSKVSVVGLGMAHQKAVAASMFRALAEANVNIHMIT--TSEIKISCLVPR--DQANEALRAVHEAFSLDQRPSDAKTWNEIKASNAKEADVADVVARLQNDALEALTLTDISIVPAQARVTLDGVPDQVGVAADMFEQIGEAGIFVDMIVQG-YDGEDGSTSVSFTVEQADLDAAQKVAREICGKHSMRDVRGASGITKLSVSGIGLRSHTQVGTVLFEQLASAGINVEMIATSELQVNVVIQSDQAGDAATRLKQAFAEALH
Mthe-3_Aa_|_CG-99   β                    MALIVQKYGGTSVN----GPERVKNVARRVVNT----RRAGNDVVVIVSAPGD--------MTDDLIAMAHEISPN-------------------------------------------------------------------------PPAREMDMLLATGEQTSIALLAMAIHELGEPVISLT--GPQVGILTDNVHSKARI------MEVSCERLRRELEQGK-----IVIVAGFQG--KTCEG--EITTLGRGGSDTTAVAVAAALKA--DVCQIYTDVDGVYTADPRVVP-EARKLPVISYDEMLE-LASLGAQVLQPRSVEFGKLNHVVLEVRSSFN------------DHEGTLVKEVT--------------------EMERKMVVSGVAGDRNVARIALHDVP---DRPGIARTLFVALARESINVDMIVQSAMR-DGIN---DIAFTVGRDDLQKAVEVTE-RVRQ--------EIGASKVTSNDRVAKVSIVGAGMITNPGVAADMFACLAEEGINIHMIS--TSEIKVSCIIDE--EHLTRAMQALHRHFKLDRE                                                                                                                                                                                                
Mxan_Ab_|_CG-99   β                    MALIVQKYGGTSVG----DVARIKSVALRCLAA----QEAGHDVVVVVSAMSG--------ETNRLMKLVAQITDR-------------------------------------------------------------------------PDEREQDVVVATGEQVSIGLLAMAIHAQQGKATSFL--GQQVRIVTDSTFAKARI------KSIDAQPIRAALARGH-----IVVVAGFQG--VDESG--SVTTLGRGGSDTTAVALAAALNA--DACEIYTDVDGVYTSDPNMVP-SARKLDRITYEEMLE-LASVGAKVLQIRSVEFAMKYKVPLWVKSSFT------------DDPGTLVCEE--------------------DSSMEDVLVRGVAYDRNEAKITVCGVP---DVAGAAAKIFGPLDEKHIVVDLIVQNPSKDG----RTDVTFTVGKADFLTAQEVVRKVAE---------EIGASGIETDGDIAKVSIVGVGMRNHSGVAARMFRALSAEGINIQMIS--TSEIKVSCVVQA--KYTELAVRALHTAFGLDQPMP-----PEGVSAVSEMAALMGEKV                                                                                                                                                                       
FRAN-2a_|_CG-99   β                    MAIIVQKYGGSSLA----TIEKIRGVARRVVDT----AAAGKQVVVVVSARGR--------TTDELLGEARALGGH-------------------------------------------------------------------------WRSRESDQLVSTGEVVSAATTALALRELGQPAVSMT--GGQAGIQVSGEFGSAAV------HSVTPDRLRTSLEEGK-----VVVVAGFQG--VDASG--DVRTLGRGGSDTTAVALAAALG---ATCEIYTDVDGVYTADPRLVP-RARLLPTVPAPLMHE-MAHTGAGILHPRAVDLAATRRIPVQVRNSLG------------TNPGTVVEVVPGN------------------PLESDGVVAAVTQDEDTTLVMMRGRG---EPLDSWAALARMASAKVAPADLFALADSTHG-----STLGFTSSPARQIDLAH------IA--------RQAGGTVELRDDLGRLSLVGTRMNLCGAVIETLAEILSTHGIRSPWIA--ISERRISILVPR--GGMRRLALTIHDALVLGRGLEAHSSDR                                                                                                                                                                                        
Sgri_Ab_|_CG-99   β           MTTQGSRPTGDVVVQKYGGSSLA----TVSQVRQVADRVGAL----ARSGRRVVVVVSAQGD--------TTDELVGRAEAVNPR-------------------------------------------------------------------------PAGHELDQLLATGETASAALMAMALQRGGLAATALS--GARSGVLATGPHGAGVI------VAVDTDQLRTLLDAGR-----TVVLAGFQG--VTAEG--DIITLGRGGSDTTAVAVAAELRS--GHCEIYSDVPGVFTADPRVVP-DARLMPDIDIDVMTE-MAFAGARVMHARAVELAALYDVDILVGRSTA------------TRTGTRIHRRDGND-----------------MLEDRTAVSAVVHDADIARITLRTHD---TP-DPSADVFRFLAKESIPADMTTVSSAPDGG----FSLGFTVRRSHAADVGRSFS-DLMA--------PRPHG-VEVEDQVAKVSIVGQGLLSRPEYASRMLASLVGSGISARSLT--ASQLRVSVTVPR--SDAVRAVGLLHSEFGLGAEAGAVPASLTPRP                                                                                                                                                                                    
Twhi_Aa_|_CG-99   β                    MSLIVQKYGGSSLA----SANNLKRVAERVSRA----YYGNNRLVVVVSAMGS--------TTDRLLTLAHEVSVE-------------------------------------------------------------------------PERRELDVLLSTGECVTASLLAMAINSIGLPARSFT--AAQAGIVTDEHHCNARI------ITITPTLIEDALNAGE-----IAVVAGFQG--VNRKG--QVTTLGRGGSDTTAVALAAALKA--DRCEIYSDVEGVFTADPRIVP-KARLLESIPIDHMLE-LSTAGARILSLRSVVFAKRHNVSVKVGSTFS------------DTSGTILCN--------------------EGEAMEEPVITGIATDTSQARITIVGLP---DIPGSAAEVFSALSVAEVAVDNIVQNFSSSNT--GFIDLSFTSPKAQGPAVTSALRENQT---------RIGYKDLQYDDEVGKITVVGSGIQHSADISAQLFRLLSDAKVNVEMIS--TSEMRISFVVRA--NVVAEVARLIHTSFGLDA------------DLRAVVHS-EGRV                                                                                                                                                                        
Rxyl_Ab_|_CG-99   β         MERRHRQRERPLGIVVQKYGGSSVA----TAEHIKAVAGKIQRA----RKAGLDLVVVASAMGK--------TTDRLLRLAGEVSSD-------------------------------------------------------------------------PSPREIDQLLATGEEQSVALLAMALHDRGVPAVSLT--GPQAGMRATGRYGSGVI------SEIRPGRIRRLLGEGR-----VVIVAGFQG--MNALG--DVMTLGRGGSDTTAVALAAALGA--DRCEIYTDVDGVYTADPRIVP-GARRIPVISYAEMSE-MAWRGAKVMHPRAVELGALYGVEIHVLSSFDEE-----------SPGTIITGGEK-----------------VEHLETRETVAGIVHDTDVARITLNGVR---TGPGTLSKVFTPLAERGISVDVIVESGIK-EGVA---DIAFTVSRADFAEARSAAG-EVAR--------ALGG-SVEGEEGLAKVSVVGTGMLNRPGYAARMFSALGSEGIPIRMVS--TSEIQVTCVIPA--ERVQEAVRRLHRDFELEEREDV                                                                                                                                                                                             
Aaeo_Aa_|_CG-99   β                    MKILVQKFGGTSVG----TLERIELCAKRVIKA----LEKGYKPVVVSSAMAG--------ETDSLIELAKKVHPR-------------------------------------------------------------------------PPEREMDTLLAVGEQKAIALFAMTLNKLGYPAVSLC--GWQVPIITDNVHTKARI------RKIGISRLLSLIEEGY-----IPVVAGFQG--VTEDW--EITTLGRGGSDTTAVALAAALKA--D-CEINTDVPGVFTADPRIVP-NAKKIKKISYEEMLE-LASLGAKVMQIRSVEFAAKYNVRIHVRSTFS------------EEEGTWIVPE--------------------DEVMEKVAVRGITVDTKETRFTVVRVP---DKPGIAAEIFKALGDAHIVVDMIVQN-VSHE---GYTDMSFTVNKTDADKAEEIVKKIAQ---------KIGAKEVVRDDKVAKISIVGIGMKSAYGVAGRMFDILARNGINIKAIS--TSEIKISCLIDE--KYAELAVRALHEEFIEEMEEF-----ETINGKNKE                                                                                                                                                                                
Sthe-17_Ab_|_CG-99   β                    MGLVVQKFGGSSVA----TAEKYRRVARRIAWK----KRQGNDVVVVVSAPGD--------MTDDLIERARSITDR-------------------------------------------------------------------------PSAREMDVLLATGEQISIALLTMALHELGVDAVSLT--GPQAGFQTDDHHRAARI------VNIDTARIRRELAAGR-----VVIVAGFQG--MDDHG--DITTLGRGGSDASAIALAAYLSA--DQCQIFTDVDGVYSADPRIVP-TARRLDEISYDEVLE-LAAAGAQVMQLRSVELAKQYGVEFEVLSSLAPLPD-----EGGEERGTKVVAKL--------------------SPNNHRIVSGVAVDSKVAHITLLGLP---DRPGVAYRAFKALGDARINLDMIVQSAGTGCGNGPTADISFTCARDDLETALEVCN-RLLP--------EFPGARVVYDTDVAKVSIVGSGVASNYGVAARMFEALAEKDINIELIT--GSEIKISCLVRA--SRAMEAVRAVHDKFELGDVAPIVQ                                                                                                                                                                                           
Tthe_Aa_|_CG-99   β                    MALVVQKYGGTSVG----DLERIHKVAQRIAHY----REKGHRLAVVVSAMGH--------TTDELIALAKRVNPR-------------------------------------------------------------------------PPFRELDLLTTTGEQVSVALLSMQLWAMGIPAKGFV--QHQIGITTDGRYGDARI------LEVNPARIREALEQGF-----VAVIAGFMG--TTPEG--EITTLGRGGSDTTAVAIAAALGA--KECEIYTDTEGVYTTDPHLIP-EARKLSVIGYDQMLE-MAALGARVLHPRAVYYAKRYGVVLHVRSSFSY------------NPGTLVKEVA---------------------MEMDKAVTGVALDLDHAQIGLIGIP---DQPGIAAKVFQALAERGIAVDMIIQ-GVPGHDPS-RQQMAFTVKKDFAQEALEALE-PVLA--------EIGGEAILR-PDIAKVSIVGVGLASTPEVPAKMFQAVASTGANIEMIA--TSEVRISVIIPA--EYAEAALRAVHQAFELDKA                                                                                                                                                                                                
Chyd_Aa_|_CG-99   β                     MLVVQKYGGSSVA----NPERIKNVARRVAEY----YRAGHRVAVVVSAMGD--------TTDELLDLMGEISPN-------------------------------------------------------------------------PPAREIDMLLSTGEQVSVALLAMALHELGVPARSFT--GLQAGIYTDEVHTKARI------TEIKPERVIACLNSGK-----VAVVAGFQG--VNREG--DITTLGRGGSDTTAVALAAALKA--DICEIYTDVDGVYTADPRIVP-DARKIKEISYEEMLE-LASLGAVVLQPRSVDFARNYKVEVHVRSSFN------------YNEGTVLKEER--------------------DLEKKGVVTGVAHDKNVVKIGVFGVP---DQPGVAYRLFSELAAHNINVDMIIQSAGKEEGQN---DISFTIGKNDLAKTVEILE-DVVK--------KLSARGYTYDEKVAKVSIVGAGMVTYPGVAAKMFEALYEENINIQMIS--TSEIKVSCIIAE--DAVERAVNAIHKKFELGNGV                                                                                                                                                                                               
Swol_Aa_|_CG-99   β                    MSLIVAKFGGSSVA----SIDKIKHIAGRIKGM----RDKGDDIVVVVSAMGD--------TTDELIELASLTGHD-------------------------------------------------------------------------LCKREMDMLLATGEQQSAALLALTLNNFACSSISLT--GWQAGIKSDDSHSKARI------TGIETGRIKNELKQGN-----VVIIAGFQG--LSPQG--DITTLGRGGSDTTAVALAACLDA--LRCMIFTDVEGVFTADPRIVK-EAKKLPQISYEEMLE-MASLGAGVLQPRAAEFAMLYNVDVEVLSSFS------------HNPGTIITEVA--------------------NMENHRAVSGIAHDLNCARFALFDVP---DQPGIAKTLFKTLAAENINVDIIIQSAMR-DGRN---DIAFTIEEKELSRAIPVVE-GLVK--------KICASGMTYGNDVAKVSIVGAGMQSNIGVAAAMFEALADEGINIHMIS--TSEIRVSCVIDE--CHIKAAIKALHRKFELDKIE                                                                                                                                                                                               
Pubi_Aa_|_CG-99   β                    MKTVVLKFGGTSVG----SIDRIKSVAKIISSY----KKKKMGVIVVSSAMSG--------TTNELIKKTKELSNT-------------------------------------------------------------------------FDAAEYDVLLATGEQATCALIAGRLKHLGFKARSWM--SWQLPIITEGPYSSSRI------SKINKGKIL-SFMKSGG----IPIITGFQG--INLEN--RLTTLGRGGTDASAIMLAKFFNT--DACDIYTDVDGVYTTDPRNHS-KAKKIHKISYDEMLE-MASLGAKVMQPTSVQDAKLNNINFSVKSSFQ------------KKKGTLITGTK--------------------KTFSNQIITGITSTKNDSKVTIVGVK---DRPGVAAAVFKPLSLNQINVDMVVQNISLNGK---ETDLTFTIKSEDVKKTEKIIKQNKR---------ISFR-KLTYDNNVSKVSIIGVGMITTPGITYRMFQALASKKINIMVIS--TSEIKISVLISN--KQIKKAVAVLHKEFKLD                                                                                                                                                                                                  
Sfum_Aa_|_CG-99   β                    MALVVQKYGGTSVA----NPERIKAVAEKVVGR----RRKGDDLVVVLSARAG--------ETDRLIALAHEVSLS-------------------------------------------------------------------------PDAREMDVLLATGEQTTVALFSMAVRNLGVEAISMT--GYQAGINTDRSYGQARI------SGIETRPIMEKLHEGR-----IVVVAGFQG--YDDEG--NITTLGRGGSDTTAVALAAALGA--DVCEIYTDVEGVFTADPNVYS-KARKLDRISYEEMFE-MASMGAKVLHLRSVEFGMKYHVPIMVLSSFT------------DAPGTLVTKE--------------------DEEMEKVVVSGITYNKNEGRITITNVP---DQPGMAARVFRPISDAGINVDLIVQSGAGIP---GRADISFTVPKTAHKKAMEIVEAVAR---------EIDAGPVHGNASIAKISIIGLGMRNHSGVAAKMFDSLARENINLKMIS--TSEIKISCIIEE--KYAELAVRVLHDAFELETAPH-----GRIEVQEET                                                                                                                                                                                
Phal_Aa_|_CG-99   β                    MALIVQKFGGTSVG----SIERIEAVADLVVKT----KQQGHQVVVVLSAMSG--------ETNRLINLAKQIDTR-------------------------------------------------------------------------PSSRELDVLISTGEQVSVALLAMAIIKRGHSAVSLL--ADQVNILTDNMFGKARI------TDVAATRLKHELEHNR-----IAIIAGFQG--RDIEG--NVTTLGRGGTDTSAVEIAGAIKA--DECQIYTDVNGVYTTDPRVEP-NARRMSQVTFAEMLE-LASLGAKVLHIRSVEAAGKHNVPLRVLSSFY-----------PD-AGTLIS-FE-------------------ESDMPGNVVSGIAFNRDECLINVEGVL---SGTQYLAKILKLFADNGIEIDMINQVNHNV----DKVDYAFTVHTNDYLHALDVLTEQQA---------QLTAQNIFGLTTVAKVSAVGMGMKSHSGVASLFFDALAAENINVILVS--TSEIKISVLIDE--KYLELAVRALHKIFLTEN------------E                                                                                                                                                                                    
Ping_Aa_|_CG-99   β                    MALLVQKYGGTSVG----NIERIKSVAEKIKAT----KADGHDVVVVLSAMSG--------ETNRMIALAKEITAN-------------------------------------------------------------------------PSPREMDVLLTTGEQTTIALLSMALHSLGLDAVSMT--GDQIRLKTDSCHSKARI------LDVETKNIKEHLKLGR-----VVVVAGFQG--RSETN--EITTLGRGGSDTSAVAIAAALKA--DECQIYTDVDGVYTTDPRVEP-NARRLDRITFEEMLE-MASLGAKVLQIRSVEFAGKYNVPLRVLSSF------------KDGGGTLICYE--------------------ENKMESPVISGIAFNRDEARLTLSGVP---DKPTVAAQILSPIGDANIDVDMIVQNTLGN----GKTDFTFTVHRDDYEQTKELLEKVCV---------LLHADNVQGNKEIAKVSVVGVGMWNHPGVAKTMFETLGQEGINMHQIA--TSEIKISVLVDS--KYLELAVRALHKAFKLAD------------DPTEEK                                                                                                                                                                               
Dnod_Aa_|_CG-99   β                    MALIVQKYGGTSMG----SVERIETVADRIVRA----RQAGHDVVVTVSAMSG--------ETNRLIALAQRFAAQ-------------------------------------------------------------------------PSPRELDVLMSSGEQVSMALLAIALEKRGCPALSLA--GWQVGIFTDSQHTKARI------QHIDDGAIYRALSAGK-----VVIVAGFQG--VDEAG--DITTLGRGGSDTTAVALAAVLKA--DECQIYTDVDGVYTTDPRIEP-RARKLEQISFVEMLE-MASLGSKVLQIRSVEFAGKYHVPVRVLSSFS-----------DDETGTLISSVE-------------------GAIIEATHVTGIAFTRDEVMIQLMHLP---DDMNTLYQILRPIGCADISLDMVAQTRNDD----GSINFSFIVPHQEKDRVIEFIVEQFS---------HIAALSVL-QTEIAKISLVGLGLRSHTGIIGRILQALMQENIPVHCFA--TSETRVSLVTDL--LYLERAVHCLHDAFQLEK------------ADECRESF                                                                                                                                                                             
Cbur_Aa_|_CG-99   β                    MALIVQKFGGSSVA----NLEGIQNVARLISEA----RQEGHSVVAVVSAMYG--------ETDRLIKLAQSISG--------------------------------------------------------------------------SNWREYDALISTGEQVSAALLSMALEARNCPAHSYT--AAQIRLRTTNEHKKARI------VDIDPEILHSDLKEGR-----VPVVAGFQG--VSDAG--DITTLGRGGSDLTAVALAAALEA--DECQIFTDVDGVYTSDPKIVP-QARRIPKITFDEMME-MSSLGAKVLQNRCLEFAGKFKVPVRVLSSLR------------KGPGTLITFEW--------------------DSAEQPLVSGIAFDRRQAKLTIQGIP---ERPGLASYILGPISKANIEVDMIVQNVPTID---ANIDFSFTLPRDDYKDAFSIMKQVAN---------ELAAGAVLGSDQVAKISLVGVGMRSHAGIASQMFSALGQEGIHIHLIT--ATEVKISAVIDE--KYLELGARTLHSAFKLNQ------------EIKFT                                                                                                                                                                                
Mcap_Aa_|_CG-99   β                    MALFVHKYGGTSVG----SPERIKNVAKNVIRA----RSRGDDIIVVVSAMSG--------ETNRLVALAHEMHER-------------------------------------------------------------------------PSTREMDVLLATGEQVTIALLSMALEAAGCPACSYT--GGQVRILTDDAHTKARI------LDIDTDRIRSDLAAGR-----VVVVAGFQG--ITEAG--DITTLGRGGSDTTAVALAAALKA--DECLIYTDVDGVYTTDPRIEP-KARRLDRITFEEMLE-MASLGSKVLQIRSVEFAGKYNVPLRVLSSF------------AAGPGTLITYE--------------------EASVEKPLISGIAFNRDEAKLTVKGVP---DKPGVAYQILGPVAHANIEVDMIVQNVAED----ATTDFTFTVHRNDYRKALDILQATCT---------ALGAREVTGDDKIVKVSLVGVGMRSHAGIAARMFEALAREGINIRMIS--TSEIKISIVVDE--KYLELAVRTLHEAFNLDR------------EPDAV                                                                                                                                                                                
Csal_Aa_|_CG-99   β                    MALYVQKFGGTSVG----SVERIKAVAEKVKRF----RDEGHQVVVVVSAMSG--------ETNRLIDLASQINDE-------------------------------------------------------------------------PTPREMDMLVSTGEQVTISLLAMALHKLDVEATSYT--GAQVGIRTDSAHTKARI------QRIETDDIQADLDDGQ-----VVVVAGFQG--VDDEG--NITTLGRGGSDTTGVALAAALKA--DECQIYTDVDGVYTTDPRVCS-KAQRLSAITVEEMLE-LASLGSKVLQIRAVEFAGKYNVPLRVLSSF------------EDGPGTLIVAEE------------------EETTMEEPLISGIAFTASEAKLTLLNTP---DVPGVASKILGPIADANIEIDMIVQNVAPAG---DYTDFTFTVAKSDYKQTKSILQDQVIP--------ALGGGELRGDDNIAKVSLVGVGMRSHAGVASKMFRVLADENINIRMVS--TSEIKISVVIDE--KQMELAVRALHTAFGLDK------------DSIQGE                                                                                                                                                                               
Tcru_Aa_|_CG-99   β                    MALIVQKYGGTSVG----NVERIQNVADKVAKF----IDEGHQVVVTLSAMSG--------ETNRLTALAKEVQEQ-------------------------------------------------------------------------PSRREMDVLLTTGEQVTIALLSMALQQKGYDSISYT--GWQVPIKTNDIHSKARI------EEIDSDKIRNQLDQGK-----VVVVAGFQG--VTPEG--DITTLGRGGSDTTAVALAAALKA--DECQIYTDVDGVYTTDPRVVP-EAKRLDVVTFDEMLE-LASLGAKVLQIRSVEFASKYKVPLRVLSSM------------KEGGGTLLISEEDF----------------EDLDMEKPLISGIAFSRDEAKLMILGVP---DKPGVAYQILGPISDANIEIDMIIQNQSVD----GTTDFTFTVARGDLHAAQKILEKTAE---------SLGAREVICDDTIVKISMVGVGMKSHSGIASTMFKTLADHNINIQMIG--TTEIKISVVIEE--SYLEEAVQALHAAFELDK                                                                                                                                                                                                 
Crud_Aa_|_CG-99   β                     MIIIQKFGGTSVG----TKKRIKSLKNIIKKY----RNLNIRIVIILSAMSG--------ETTKMLRLAKYFKYK--------------------------------------------------------------------------KLKSIDFMLCIGEQMSVSLFNLLLNSVKILSIPLI--SSQIGFITNNNYSNARI------ILIKNIVLIKKILKKKQ----IPVLTGFQG--ITLNG--NLTTLGRGGSDTSAVAISIYLKA--TECQIYSDVKSIFVSDPRICL-NYR-INFLPFENMLE-LSSLGSKILFVRSIELARKYNVNIRLLSSFF------------KKKGTFISKKKKF-----------------VNSMERVLISGISYTSNEVKITVANIP---NVSGVLSKILGPIISNGICIDMVIQNSLNHLK---FTNFTFLIEEFFLKKVIFLIKKFFI---------TKIGGRVEYEKHISKVSVIGIGLRSHNYIIGKIFYSMSKLGINIILVS--TSETKISILIKK--KFTVLAIKNLYKIFNKQFFVKRNG                                                                                                                                                                                           
MAGN-2a_|_CG-99   β               MKRVDVALIVLKFGGTSVG----SIERIRNVARMAMAE----QQAGNQVVVAVSAMSG--------ETNRLVGLVEDLTQF-------------------------------------------------------------------------YNKREYDVVVSAGEQISIGLLATAIESMGQKAKSYL--GWQVRFITDGSHSKARI------KEVEAFRIQADLDAGA-----IVIVAGFQG--VDSHN--NITTLGRGGSDTSAVALAAALKA--DRCDIYTDVDGVYTTDPRIVT-KARKMDRISYDEMLE-LASLGAKVLQTRSVELAKKYSVPVRVLSSLE------------PGSGTMLTKE--------------------EDTMESVVVSGLAYDKNEAKITILGVP---DKPGVAANLLGRLGDANINIDMIVQNVSPAG---DATDMTFTVPKADFPQAMKVMEDAVK---------DVGARQLQGNSDIAKISAVGVGMRSHSGIAQKMFKALADEGINILMIS--TSEIKISVVIEE--KYTELAVRALHDAFELEK------------DPSDRINA                                                                                                                                                                             
           
Faln_Aa_|_CG-99   β                  MAGDVVVLKFGGAAFAAPGAHQGIARHVADRLRAGGSSASPGGARAIVVVSAVAG--------ETDRLGTALRAVSPA-------------------------------------------------------------------------PDRDLLAAALMTGETVNVALMTAALRDAGLAAVALT--AADTGFVGAGEPHCADLR------RIDGSVLASLVEPAG----TVLVVPGGQA--VDGDG--RPIMLGRNSSDLSAIAAAIAVGA--RACEIFSDSPGICTADPRLVP-DARTLAAVDYDTMIT-MSRHGAKVLHHSAVAWAQRHGVEIRCRSLLP--------------DG------------------------------AVYSVVRAGRTSAAAVLVHGTGTVWAGDPDLVRATLAELGSDAVAIPEAAAVPEVAVT------EVAAVPEVAAVPDVAVTDVAVT---------EVAVTEVAAAAATAGIAGTAAVGEPVGGTVAHLVLADAARDLRPRGLRHRADLRLVTTLFPD--GRLQHRLVPAAEAPTVARAQHDVVVA                                                                                                                                                                                         
           
Consen1   Primary consensus                        V KfGGtSv ----               ----         v SA   -------- Td L           --------                                                       ---------      d l s GE  s  l a  l           --       t         ------                     v v  GF g--      -    LGRGGSD tA  la  l  --    iytDV Gv taDP    - a  l  i   em e-la  Ga vl   sv       i l v  s   ----------    GT i     -----------------         v  i        i      -           f            i         ---                          -- -----               vs vG  m                         --     i  vi  --         lh                                               I     Q  V     PD  GVAA       E     D IVQ            SFT    D   A         K           I K S  G G           F  LA   IN EMIATSE              A       F     
Consen2   Secondary consensus                           y  s                                   i                n                                                                            e              a         t       i                                   n                       i     a                     s    g             s    i s         t         qa a ms   s i             v                                 f                                                        l                      n g                          el                        i                             qg                        y                                                                                                                                                                                                        

Consensus 1 (when a gap)
Conservative difference
Consensus 2 (when a gap)
Nonconservative diff.
Other character