Home of the SEED

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Home of the SEED

With the growing number of genomes becoming available, a software environment is needed to produce accurate and consistent annotations.

The SEED is that environment, we provide a read-only copy of the SEED environment with the latest data and annotations. For users interested in editing and learning how to use the system, we also provide a public SEED.

The annotation is performed not on a gene by gene basis per genome, but rather by subsystem by an expert curator across many genomes at a time.

  • You can download software and data from our Download page.
  • We provide a list Glossary of terms used.
  • When using the SEED, please cite: Overbeek et al., Acids Res 33(17), 2005
  • Ross Overbeek laid out the strategy for the annotation of the first 1000 genomes.
  • Our approaches to annotation, gene calling etc are outlined in a series of Standard Operating Procedures.