https:/// /w/index.php?action=history&feed=atom&title=SpecialPurposeDBs 2026-05-14T10:02:15Z Revision history for this page on the wiki MediaWiki 1.35.6 /w/index.php?title=SpecialPurposeDBs&diff=2472&oldid=prev 2009-01-06T15:39:21Z

<p></p> <table class="diff diff-contentalign-left diff-editfont-monospace" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 15:39, 6 January 2009</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1" >Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">== HOPS Database ==</del></div></td><td colspan="2"> </td></tr> <tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">('''H'''ypotheses and '''O'''pen '''P'''roblems revealed by '''S'''ubsystems)</del></div></td><td colspan="2"> </td></tr> <tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr> <tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Sequencing and analysis of hundreds, soon to be thousands, of genomes reveals multiple gaps in our knowledge of basic biochemical and cellular processes. Accurate mapping of the revealed open problems within a framework of specific subsystems and groups of organisms sets the stage for generating hypotheses amenable to experimental validation. In a growing number of cases, predictions of novel genes and pathways delivered by comparative genomics techniques (eg analysis of gene clustering on prokaryotic chromosomes) get successfully verified. </del></div></td><td colspan="2"> </td></tr> <tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr> <tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">[http://www.theseed.org/HOPSS/HOPSS.cgi HOPS Database]</del></div></td><td colspan="2"> </td></tr> <tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr> <tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr> <tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== EGGS database: Essential Genes on Genome Scale ==</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== EGGS database: Essential Genes on Genome Scale ==</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l12" >Line 12:</td> <td colspan="2" class="diff-lineno">Line 4:</td></tr> <tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>SEED maintains an up-to-date database of all microbial gene essentiality data experimentally obtained in the currently published genome-scale gene essentiality screens (listed in Table 1). Comparative analysis of these data across multiple organisms in a rich genomic, biochemical, and phylogenetic contexts provided by the collection of annotated Subsystems greatly facilitates their interpretation and practical applications, such as, understanding of cellular networks, gene and pathway discovery, identification of novel drug targets, and strain engineering.</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>SEED maintains an up-to-date database of all microbial gene essentiality data experimentally obtained in the currently published genome-scale gene essentiality screens (listed in Table 1). Comparative analysis of these data across multiple organisms in a rich genomic, biochemical, and phylogenetic contexts provided by the collection of annotated Subsystems greatly facilitates their interpretation and practical applications, such as, understanding of cellular networks, gene and pathway discovery, identification of novel drug targets, and strain engineering.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[http://<del class="diffchange diffchange-inline">theseed</del>.<del class="diffchange diffchange-inline">uchicago</del>.<del class="diffchange diffchange-inline">edu</del>/FIG/<del class="diffchange diffchange-inline">eggs</del>.cgi EGGS Database]</div></td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[http://<ins class="diffchange diffchange-inline">www</ins>.<ins class="diffchange diffchange-inline">nmpdr</ins>.<ins class="diffchange diffchange-inline">org</ins>/FIG/<ins class="diffchange diffchange-inline">wiki/view</ins>.cgi<ins class="diffchange diffchange-inline">/Main/EssentialGenes </ins>EGGS Database]</div></td></tr> </table>

Marland /w/index.php?title=SpecialPurposeDBs&diff=1491&oldid=prev 2006-10-13T21:49:31Z

<p></p> <p><b>New page</b></p><div>== HOPS Database ==<br /> ('''H'''ypotheses and '''O'''pen '''P'''roblems revealed by '''S'''ubsystems)<br /> <br /> Sequencing and analysis of hundreds, soon to be thousands, of genomes reveals multiple gaps in our knowledge of basic biochemical and cellular processes. Accurate mapping of the revealed open problems within a framework of specific subsystems and groups of organisms sets the stage for generating hypotheses amenable to experimental validation. In a growing number of cases, predictions of novel genes and pathways delivered by comparative genomics techniques (eg analysis of gene clustering on prokaryotic chromosomes) get successfully verified. <br /> <br /> [http://www.theseed.org/HOPSS/HOPSS.cgi HOPS Database]<br /> <br /> <br /> <br /> == EGGS database: Essential Genes on Genome Scale ==<br /> <br /> SEED maintains an up-to-date database of all microbial gene essentiality data experimentally obtained in the currently published genome-scale gene essentiality screens (listed in Table 1). Comparative analysis of these data across multiple organisms in a rich genomic, biochemical, and phylogenetic contexts provided by the collection of annotated Subsystems greatly facilitates their interpretation and practical applications, such as, understanding of cellular networks, gene and pathway discovery, identification of novel drug targets, and strain engineering.<br /> <br /> [http://theseed.uchicago.edu/FIG/eggs.cgi EGGS Database]</div>

DanielPaarmann